Inactive Matrix Gla-Protein and Arterial Stiffness in Type 2 Diabetes Mellitus
نویسندگان
چکیده
منابع مشابه
Treating Arterial Stiffness in Metabolic Syndrome and Type 2 Diabetes Mellitus
Arterial stiffening characterizes ageing and several diseases related to increased cardiovascular (CV) risk such as the metabolic syndrome (MetS), type 2 diabetes mellitus (T2DM), hypertension, obesity and smoking. Several studies have shown that arterial stiffness is a strong, independent predictor of CV morbidity and mortality risk in such patient populations. Lifestyle measures and drugs fre...
متن کاملEffect of vildagliptin on hsCRP and arterial stiffness in patients with type 2 diabetes mellitus.
OBJECTIVE To evaluate the effect of dipeptidyl-peptidase-4 (DPP-4) inhibitor vildagliptin on high sensitivity C-reactive protein (hsCRP) and arterial stiffness (AS) in patients with type 2 diabetes (T2DM). DESIGN Sixty-four drug-naive diabetic patients, with inadequate glycemic control, participated in this randomized, open-label study. Half of the patients received metformin 1700 mg/d and th...
متن کاملErratum: Vascular calcification in patients with type 2 diabetes: the involvement of matrix Gla protein
Corrections Following publication of our article [1], it has come to our attention that Olivier Bourron’s name was displayed incorrectly. We publish this correction to update the author list, which is as follows: Sophie Liabeuf , Olivier Bourron , Cees Vemeer , Elke Theuwissen , Elke Magdeleyns , Carole Elodie Aubert , Michel Brazier , Romuald Mentaverri , Agnes Hartemann , and Ziad A. Massy 1,...
متن کاملVascular calcification in patients with type 2 diabetes: the involvement of matrix Gla protein
BACKGROUND Matrix Gla protein (MGP) is an important inhibitor of calcification. The objective of the present study of patients with type 2 diabetes and normal or slightly altered kidney function was to evaluate levels of inactive, dephospho-uncarboxylated MGP(dp-ucMGP) and total uncarboxylated MGP(t-ucMGP) and assess their links with biological and clinical parameters (including peripheral vasc...
متن کاملAcarbose treatments improve arterial stiffness in patients with type 2 diabetes mellitus
UNLABELLED Aims/Introduction: Although the improvement of postprandial hyperglycemia by an alpha-glucosidase inhibitor (α-GI) has been associated with a risk reduction of cardiovascular events, the relationship between postprandial hyperglycemia and arterial stiffness has not been well understood. We therefore examined whether ameliorating the postprandial state by α-GI leads to an improvement...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 2016
ISSN: 0895-7061,1941-7225
DOI: 10.1093/ajh/hpw146